Alice is a scientist. She lives in Geneva. As the Large Hadron Collider starts up in 2008, she is on the brink of the most exciting work of her life.

Jenny is her sister. She lives in Luton. She spends a lot of time Googling.

When tragedy throws them together, the collision threatens them all with chaos.

Lucy Kirkwood’s wildly ambitious play is a brilliantly funny and occasionally brutal exploration of the workings of the universe and our place within it and what it means to be a sister, a mother and a daughter.

With its strong debate about the merits of vaccination and the limitations of science, this production – the play’s first UK revival since its premiere at the National Theatre in 2017 – offers a particular resonance in the context of the global pandemic and the ongoing climate change debate.

Since her debut in 2008, Lucy Kirkwood has firmly established herself as a leading playwright of her generation, the writer of a series of savagely funny, highly intelligent and beautifully observed plays that tackle the pressing issues of our times including Chimerica, The Children and The Welkin.